Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Saturated Fat
0.5 g
3%**
Cholesterol
10 mg
3%
Fish Oilprovides 360 mg of Total Omega-3 Fatty Acids†comprising of:EPA (Eicosapentaenoic Acid)DHA (Docosahexaenoic Acid)Other Fatty Acids
1,200 mg (1.2 g)
***************
Top Medical Research Studies
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Read More
8
We conducted a study to see if omega-3 fatty acids, specifically sourced from Clupeonella grimmi fish oil, could help alleviate back pain associated with dysmenorrhoea. Our research involved a cross-over trial with 36 young women aged 18-22 years.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Read More
8
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
Read More
Most Useful Reviews
10
No leg pain
4 people found this helpful
These softgels are fantastic and do the job well. I used to suffer from pain in my legs, but since taking this fish oil, I no longer experience any pain. I can now bend down to clean the cat litter with ease. I wouldn't go back to the 1200mg fish oil as it caused my legs to hurt again.
Read More
7.5
Eliminated back pain
1 people found this helpful
Triple Strength is remarkable. I often hear complaints about fish oil capsules tasting too fishy, but these are splendid. They seem to have alleviated my back muscle pain. Additionally, I take them for my high triglycerides.
Read More
7.5
Less pain
Bought at a significant discount and very pleased with the quality and quantity. I've been taking three tablets daily for four months, and I recommend them. They have noticeably improved my health and reduced my back pain.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.4
- All Researches
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Read More
8
We investigated whether l-serine and EPA could help relieve chronic low-back and knee pain in adults. In a well-structured study with 120 participants, half received a combination of these compounds while the other half received a placebo. After eight weeks, results showed that those taking l-serine and EPA experienced significant pain relief.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
Read More
8
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
Read More
8
We conducted a study to see if omega-3 fatty acids, specifically sourced from Clupeonella grimmi fish oil, could help alleviate back pain associated with dysmenorrhoea. Our research involved a cross-over trial with 36 young women aged 18-22 years.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Read More
7
We explored the link between omega-3 fatty acids and various pain conditions in a study involving 605 adults. Despite high expectations, our findings revealed that a higher intake ratio of omega-6 to omega-3 fatty acids was associated with increased pain intensity, including low back pain.
Notably, higher levels of the omega-3 docosahexaenoic acid (DHA) seemed to have a protective effect, indicating that bolstering omega-3 intake might help reduce pain levels. However, the study did not show strong evidence that omega-3 fish oil directly alleviates back pain specifically.
Notably, higher levels of the omega-3 docosahexaenoic acid (DHA) seemed to have a protective effect, indicating that bolstering omega-3 intake might help reduce pain levels. However, the study did not show strong evidence that omega-3 fish oil directly alleviates back pain specifically.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
10
No leg pain
4 people found this helpful
These softgels are fantastic and do the job well. I used to suffer from pain in my legs, but since taking this fish oil, I no longer experience any pain. I can now bend down to clean the cat litter with ease. I wouldn't go back to the 1200mg fish oil as it caused my legs to hurt again.
Read More
7.5
Eliminated back pain
1 people found this helpful
Triple Strength is remarkable. I often hear complaints about fish oil capsules tasting too fishy, but these are splendid. They seem to have alleviated my back muscle pain. Additionally, I take them for my high triglycerides.
Read More
7.5
Less pain
Bought at a significant discount and very pleased with the quality and quantity. I've been taking three tablets daily for four months, and I recommend them. They have noticeably improved my health and reduced my back pain.
Read More
Frequently Asked Questions
7.5
Less pain
Bought at a significant discount and very pleased with the quality and quantity. I've been taking three tablets daily for four months, and I recommend them. They have noticeably improved my health and reduced my back pain.
7
We explored the link between omega-3 fatty acids and various pain conditions in a study involving 605 adults. Despite high expectations, our findings revealed that a higher intake ratio of omega-6 to omega-3 fatty acids was associated with increased pain intensity, including low back pain.
Notably, higher levels of the omega-3 docosahexaenoic acid (DHA) seemed to have a protective effect, indicating that bolstering omega-3 intake might help reduce pain levels. However, the study did not show strong evidence that omega-3 fish oil directly alleviates back pain specifically.
Notably, higher levels of the omega-3 docosahexaenoic acid (DHA) seemed to have a protective effect, indicating that bolstering omega-3 intake might help reduce pain levels. However, the study did not show strong evidence that omega-3 fish oil directly alleviates back pain specifically.
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
8
We investigated whether l-serine and EPA could help relieve chronic low-back and knee pain in adults. In a well-structured study with 120 participants, half received a combination of these compounds while the other half received a placebo. After eight weeks, results showed that those taking l-serine and EPA experienced significant pain relief.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
7
We explored the effectiveness of omega-3 fish oil supplements as an alternative treatment for nonsurgical neck and back pain. Over a period from March to June 2004, we asked 250 patients to take 1200 mg of omega-3 fatty acids daily. After about a month, a questionnaire revealed that 60% of participants reported improvement in their overall pain and joint pain. A significant number even stopped using traditional NSAIDs, with over 88% expressing the desire to continue taking fish oil. Overall, our findings suggest that fish oil could be a safer option for managing pain without notable side effects.
8
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
7
We examined the connection between the levels of omega-3 and omega-6 fatty acids in the blood and chronic pain conditions like lower back pain. In our study of 503 adults, we found that a higher ratio of omega-6 to omega-3 was linked to increased odds of experiencing both low back pain and temporomandibular disorder.
Interestingly, while men benefited from higher levels of omega-3 causing lower pain likelihood, the same effect wasn't seen for women. Overall, our findings suggest that omega-3 could play a role in managing back pain, although the results vary by gender.
Interestingly, while men benefited from higher levels of omega-3 causing lower pain likelihood, the same effect wasn't seen for women. Overall, our findings suggest that omega-3 could play a role in managing back pain, although the results vary by gender.
References
- Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. 10.1016/j.jpain.2022.10.008
- Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Omega-6 and Omega-3 Polyunsaturated Fatty Acids in Painful Temporomandibular Disorder and Low Back Pain. J Pain. 2022;23:1724. 10.1016/j.jpain.2022.05.008
- Sasahara I, Yamamoto A, Takeshita M, Suga Y, Suzuki K, et al. l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Nutr. 2020;150:2278. 10.1093/jn/nxaa156
- NaPier Z, Kanim LEA, Arabi Y, Salehi K, Sears B, et al. Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration. Med Sci Monit. 2019;25:9531. 10.12659/MSM.918649
- Maroon JC, Bost JW. Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain. Surg Neurol. 2006;65:326.
- Lin Z, Ni L, Teng C, Zhang Z, Wu L, et al. Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis. Front Cell Dev Biol. 2021;9:745621. 10.3389/fcell.2021.745621
- Kawabata F, Tsuji T. Effects of dietary supplementation with a combination of fish oil, bilberry extract, and lutein on subjective symptoms of asthenopia in humans. Biomed Res. 2011;32:387.
- Moghadamnia AA, Mirhosseini N, Abadi MH, Omranirad A, Omidvar S. Effect of Clupeonella grimmi (anchovy/kilka) fish oil on dysmenorrhoea. East Mediterr Health J. 2010;16:408.
